JSCDH-D-16-00022, Huy Tran
Gender-specific Analgesic Effect of Serotonin-Norepinephrine Reuptake Inhibitor in sickle mice.
JSCDH-D-16-00046, Nagavedi S Umapathy
β-nicotinamide adenine dinucleotide (β-NAD) prevents the lipopolysaccharide-induced endothelial barrier dysfunction and mortality in sickle mice
JSCDH-D-16-00012, Josh Lehrer-Graiwer
GBT440, a novel HbS polymerization inhibitor, increases Hb oxygen affinity and results in a rapid improvement in hemolysis and anemia
JSCDH-D-16-00054, Peter Buontempo
SANGUINATE-Mediated Transfer of Oxygen and Carbon Monoxide Can Rapidly Unsickle Red Blood Cells and Reduce the Systemic Inflammatory Response
JSCDH-D-16-00075, Tanya David, PhD
Novel Analogs of Ethacrynic Acid as Potential Antisickling Agents
JSCDH-D-16-00036, Oluwabukola Gbotosho
The Oxidant Response Transcription Factor NRF2 Mediates Heme Activation of Placenta Growth Factor Expression in Erythroid Cells, a Contributor to Pulmonary Hypertension in Sickle Cell Disease
JSCDH-D-16-00055, Martin Safo, PhD
In-Vivo Murine PK/PD of TD-7, a Novel Allosteric Hemoglobin Effector and Drug Candidate for the Treatment of Sickle Cell Disease
JSCDH-D-16-00006, Caterina Minniti, MD
Acute Myeloid Leukemia after Haplo-identical Transplantation for Sickle Cell Disease: A Case Study
